Expression in Human Ocular Surface Tissues of the GalNAc-Transferases That Initiate Mucin-Type O-Glycosylation

Abstract

Human ocular surface tissues express multiple ppGaNTase isoforms, suggesting a requirement for glycosylating diverse mucin-type substrates. However, there is no evidence to date to suggest that differences of ppGaNTase expression levels might contribute to susceptibility to dry eye disease.