Virus-like particles for enterovirus 71 produced from Saccharomyces cerevisiae potently elicits protective immune responses in mice

Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial

Luisa L. Villa, Ronaldo Lúcio Rangel Costa, Carlos Alberto Petta et al. · The Lancet Oncology · 2005 · 1.6K citations

Veterinary Medicine, Infectious Diseases, Oncology +17

Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial

Jorma Paavonen, David Jenkins, F. Xavier Bosch et al. · The Lancet · 2007 · 1.3K citations

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A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

Xiangxi Wang, Wei Peng, Jingshan Ren et al. · Nature Structural & Molecular Biology · 2012 · 401 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +12

Protein 3CD is the major poliovirus proteinase responsible for cleavage of the p1 capsid precursor

M F Ypma-Wong, Patricia Gillis Dewalt, Victoria H. Johnson et al. · Virology · 1988 · 326 citations

Life Sciences, Biology, Molecular Biology +11

Protection against lethal enterovirus 71 infection in newborn mice by passive immunization with subunit VP1 vaccines and inactivated virus

Cheng-Nan Wu, Ya-Ching Lin, Cathy S.J. Fann et al. · Vaccine · 2001 · 225 citations

Veterinary Medicine, Immunology, Infectious Diseases +14