Increased sensitivity of quinone resistant cells to mitomycin C

Mitomycins and Porfiromycin: Chemical Mechanism of Activation and Cross-linking of DNA

V. N. Iyer, Waclaw Szybalski · Science · 1964 · 569 citations

Pharmacy, Chemical Biology, Molecular Biology +16

Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones.

James H. Doroshow · Proceedings of the National Academy of Sciences · 1986 · 267 citations

Medicine, Oncology, Pharmacology +13

Preferential activation of mitomycin C to cytotoxic metabolites by hypoxic tumor cells.

Katherine A. Kennedy, Sara Rockwell, Alan C. Sartorelli · PubMed · 1980 · 219 citations

Medicine, Oncology, Pharmacology +17

Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P-450 reductase and xanthine oxidase.

Shengze Pan, Paul A. Andrews, Constance J. Glover et al. · Journal of Biological Chemistry · 1984 · 214 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +14

Comparative studies of leukemic cells sensitive and resistant to cytosine arabinoside

Ming Chu, G.A. Fischer · Biochemical Pharmacology · 1965 · 203 citations

Medicine, Cell Biology, Oncology +14