Non-adrenergic non-cholinergic relaxation mediated by nitric oxide in the canine ileocolonic junction

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.7K citations

Inflammation, Biological Activity, Endothelium-derived Relaxing Factor +8

Vascular endothelial cells synthesize nitric oxide from L-arginine

Richard Palmer, D. Ashton, Salvador Moncada · Nature · 1988 · 4.8K citations

Inflammation, Reactive Nitrogen Specie, Physiology +7

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

John Garthwaite, Sarah L. Charles, Russ Chess‐Williams · Nature · 1988 · 2.6K citations

Intercellular Messenger, Neurophysiology, Physiology +9

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

Richard G. Knowles, Richard Palmer, Salvador Moncada · Proceedings of the National Academy of Sciences · 1989 · 1.4K citations · Full text

Nitric Oxide, Rat Forebrain, Social Sciences +18

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

Richard Palmer, Daryl D. Rees, David Ashton et al. · Biochemical and Biophysical Research Communications · 1988 · 1.3K citations

Molecular Physiology, Biochemistry, Physiological Precursor +9