Concepedia

CS Coupling Using a Mixed‐Ligand Pd Catalyst: A Highly Effective Strategy for Synthesizing Arylthio‐Substituted Heterocycles

Mei Cong, Yuting Fan, Jean‐Manuel Raimundo, Yi Xia, Yang Liu, Gilles Quéléver, Fanqi Qu, Ling Peng

Chemistry - A European Journal · 2013 · 18 citations · 17 references

DOI

Concepts

Abstract

CS coupling: A variety of arylthio-substituted heterocycles can be prepared through CS coupling of the corresponding halide-substituted heterocycles by using a mixed-ligand palladium catalyst, [Pd2(dba)3]/ Xantphos/CyPF-tBu (see scheme; dba=dibenzylideneacetone). This catalytic system is extremely powerful and efficient, allowing even CCl bond activation.

References

17

Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

Carin C. C. Johansson Seechurn, Matthew O. Kitching, Thomas J. Colacot et al. · Angewandte Chemie International Edition · 2012 · 3K citations · Full text

, , +12

Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides

John F. Hartwig · Accounts of Chemical Research · 2008 · 1.9K citations · Full text

, , +15

A Novel Easily Accessible Chiral Ferrocenyldiphosphine for Highly Enantioselective Hydrogenation, Allylic Alkylation, and Hydroboration Reactions

Antonio Togni, Claude Breutel, Anita Schnyder et al. · Journal of the American Chemical Society · 1994 · 668 citations

, , +12

Electronic Effects on Reductive Elimination To Form Carbon−Carbon and Carbon−Heteroatom Bonds from Palladium(II) Complexes

John F. Hartwig · Inorganic Chemistry · 2007 · 482 citations

, , +16

Carbon−Sulfur Bond-Forming Reductive Elimination Involving sp-, sp<sup>2</sup>-, and sp<sup>3</sup>-Hybridized Carbon. Mechanism, Steric Effects, and Electronic Effects on Sulfide Formation

Grace Mann, David Barañano, John F. Hartwig et al. · Journal of the American Chemical Society · 1998 · 288 citations

, , +15