Large granular lymphoma in an FIV‐positive and FeLV‐negative cat

Abstract

ABSTRACT The clinical course of a feline leukaemia virus (FeLV)‐negative and feline immunodeficiency virus (FIV)‐positive cat affected with a large granular lymphocyte lymphoma is presented. Cyto‐logical examination showed neoplastic cells in the pleural effusion and in two abdominal masses. Bone marrow and peripheral blood were moderately involved and chemotherapy was used to control the tumour. Cytochemistry, immunohis‐tochemistry and ultrastructural studies were applied to define the cellular lineage; cytochemistry suggested a T‐cell lineage.