Journal of Clinical Neuromuscular Disease · 2007 · 49 citations · 15 references
MedicinePhysical MedicineRehabilitation MedicineMusculoskeletal RehabilitationPhysical ActivityPhysical TherapyExercise InterventionsExercise TherapyInclusion Body MyositisNeuromuscular RehabilitationPhysical RehabilitationStrength TrainingFunctional Exercise TrainingHome-based Exercise PrescriptionIsometric Muscle Strength TestingIsometric Strength TestingIsometric Strength TrainingPhysiotherapy RehabilitationSerum Creatine Kinase AssessmentSporadic Inclusion Body Myositis
ABSTRACT Objective: The objective of the study was to investigate the effects of a functional exercise program on muscle strength and mobility in a group of patients with sporadic inclusion body myositis (IBM). Methods and Materials: Seven patients with sporadic IBM were tested for muscle strength and functional capacities before and after a 16-week, patient-specific, home-based exercise program involving mild, daily, functional exercises. Results: Significant improvements in isometric strength were demonstrated in all muscle groups tested and were maximal in the hip flexor muscles. In addition, walking and stair climbing times improved in all patients. The exercise program was well-tolerated, and there was no significant change in the serum creatine kinase level following the exercise period. Conclusion: The findings of this study indicate that an individually prescribed home exercise program can be safely implemented and can result not only in significant gains in muscle strength but also in useful improvements in functional capabilities and is therefore beneficial in the management of patients with IBM.
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Treatment of inclusion-body myositis with IVIg
Marinos C. Dalakas, James M. Dambrosia, Elizabeth A. Sekul et al. · Neurology · 1997 · 350 citations
Inclusion body myositis: Clinical and pathological boundaries
Anthony A. Amato, Gary Gronseth, Carlayne E. Jackson et al. · Annals of Neurology · 1996 · 195 citations · Full text
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