Science · 1944 · 499 citations · 1 references
Life SciencesMicrobiologyPharmacologyAntimicrobial PharmacologyAntimicrobial ResistanceMedical MicrobiologyAntibacterial PharmacologyAntibacterial ResistanceAntibiotic ResistanceAntibiotic Resistance MechanismsBeta-lactam ResistanceResistance In Gram-positive BacteriaAntibiotic PurificationCoagulase-negative StaphylococciPenicillin ResistanceResistance Mechanisms In Staphylococci
A highly potent penicillin inactivator has been extracted from 7 strains of Staph. aureus (coagulase positive), all of which were naturally penicillin resistant. No such inhibitor was present in extracts of 7 penicillin sensitive strains of Staph. aureus.
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An Enzyme from Bacteria able to Destroy Penicillin
E. P. Abraham, E. B. Chain · Nature · 1940 · 1.3K citations