Comparative Effects of SPRM Asoprisnil (J867) on Proliferation, Apoptosis, and the Expression of Growth Factors in Cultured Uterine Leiomyoma Cells and Normal Myometrial Cells

Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

Philippe Kastner, A. Krust, Bernard Turcotte et al. · The EMBO Journal · 1990 · 1.5K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +14

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

Elisabetta Vegeto, Mauoucher M. Shahbaz, D X Wen et al. · Molecular Endocrinology · 1993 · 760 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells.

D X Wen, Yifeng Xu, Dale E. Mais et al. · Molecular and Cellular Biology · 1994 · 341 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Transforming growth factor-β3 is expressed at high levels in leiomyoma where it stimulates fibronectin expression and cell proliferation

Ibrahim Sozen · Fertility and Sterility · 2000 · 225 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Progesterone receptor messenger ribonucleic acid and protein are overexpressed in human uterine leiomyomas

David D. Brandon, Cynthia L. Bethea, Estel Y. Strawn et al. · American Journal of Obstetrics and Gynecology · 1993 · 211 citations

Medicine, Gynecology, Molecular Biology +14