Rapid Diagnosis of Rotavirus Infection: Comparison of Electron Microscopy and Enzyme Linked Immunosorbent Assay (Elisa)

Abstract

Roberton, D. M., Harrison, M., Hosking, C.S., Adams, L. C. and Bishop, R. F. (1979). Aust. Paediatr. J. , 15, 229–232. Rapid diaggnosis of rotavirus infection: Comparison of electron microscopy and enzyme linked immunosorbent assay (ELISA). Commonly used methods for detecting rotavirus antigen in stool are either relatively insensitive (counter‐immuno‐electrophorosis) or suitable only for research laboratories (electron microscopy). In this paper we describe an enzyme linked immunosorbent assay that compares favourably with electron microscopy in terms of sensitivity and is adaptable for use in hospitals or for epidemiological studies in the field.