Mobility of Potassium Ion in Frog Muscle Cells, both Living and Dead

Abstract

The diffusion coefficient of potassium ion (DK) in frog muscles was studied by a new method. In normal cytoplasm DK averaged one-eighth of the value in the free solution. Arrest of metabolism or injury caused an increase in DK. In muscles killed with iodoacetate, DK rose to three-quarters of the value in free solution. The data support the association-induction hypothesis.