Autoradiographic Localization of [ ³ H]Gentamicin in the Proximal Renal Tubules of Mice

Abstract

The site of localization of [(3)H]gentamicin within mouse kidney is shown to be the proximal renal tubule by coincidence of the radioactivity, as visualized by autoradiography, and the mucopolysaccharide-rich microvilli characteristic of proximal convoluted tubules, as visualized by histochemical staining.