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Novel triethylsilane mediated reductive N -alkylation of amines: improved synthesis of 1-(4-imidazolyl)methyl-4-sulfonylbenzodiazepines, new farnesyltransferase inhibitors

Medicinal ChemistryNew Farnesyltransferase InhibitorsNovel TriethylsilaneNatural SciencesMedicineOrganic ChemistryReductive N -AlkylationChemistryHeterocycle ChemistryPharmacologyPharmaceutical ChemistrySynthetic ChemistryDrug Discovery