Progress and Challenge for Magnesium Alloys as Biomaterials

TLDR

Magnesium alloys are highly biocompatible and have shown significant recent progress in bioabsorbable stents and orthopedic bone applications. The study discusses degradation, hydrogen evolution, corrosion fatigue, and erosion of magnesium alloys in simulated body fluid and proposes strategies to address these challenges for orthopedic use. The review summarizes advances in magnesium alloy biomaterials and various methods to improve their corrosion resistance.

Abstract

Abstract Magnesium alloys are very biocompatiable and show promise for use in orthopaedic implant. Significant progress of research on bioabsorbable magnesium stents and orthopaedic bones has been achieved in recent years. The issues on degradation, hydrogen evolution, and corrosion fatigue and erosion corruption of magnesium alloys and various influencing factors in simulated body fluid (SBF) are discussed. The research progress on magnesium and its alloys as biomaterials and miscellaneous approaches to enhancement in corrosion resistance is reviewed. Finally the challenges and strategy for their application as orthopaedic biomaterials are also proposed.