A highly water-soluble C₆₀–NVP copolymer: a potential material for photodynamic therapy

Abstract

Water-soluble C60 polymers, which have the highest solubility of fullerene reported to date (7.8 mM of C60 in water), were prepared via copolymerization, and showed significant visible light-induced O2*- generation and DNA cleavage, indicating the potential of these water-soluble fullerene derivatives as agents for photodynamic therapy.