Autoimmune Polyglandular Syndrome Type II Associated with Jejunal Gastrointestinal Stromal Tumor: Diagnosis by Capsule Endoscopy

Abstract

A 49-year-old woman with autoimmune polyglandular syndrome type II (Addison’s disease and hypothyroidism) was referred to our department, as she was suffering from persistent iron-deficiency anemia and had positive results from fecal occult blood test. The history of bleeding was approximately 3 years during which period she had been treated with iron supplementation. Mean Hb concentration was 8.4 g/100 ml (range 6.1-11.7). Previous diagnostic investigations had included two esophagogastroduodenoscopies, two total colonoscopies, a 99Tc-labeled red cells scan, a 99Tc-pertechnetate scan, a small-bowel follow-through investigation, and a computed tomography (CT) scan. All these tests had failed to identify the source of bleeding.