Immunodominance and antigenic variation of the principal neutralization domain of HIV-1

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

Françoise Barré‐Sinoussi, Jean‐Claude Chermann, FA Rey et al. · Science · 1983 · 6.9K citations

Life Sciences, Microbiology, Molecular Biology +16

Rapid and simple method for purification of nucleic acids

René Boom, C. J. A. Sol, M M Salimans et al. · Journal of Clinical Microbiology · 1990 · 5.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +14

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.

H. Mario Geysen, Rob H. Meloen, S J Barteling · Proceedings of the National Academy of Sciences · 1984 · 1.5K citations · Full text

Life Sciences, Biochemistry, Immunology +17

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

C K Leonard, Michael W. Spellman, L Riddle et al. · Journal of Biological Chemistry · 1990 · 980 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

<i>Trans</i> -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

Joseph Sodroski, C A Rosen, William A. Haseltine · Science · 1984 · 777 citations

Life Sciences, Molecular Biology, Molecular Genetics +17