Concepedia

Phase 1 first-in-human clinical study of S-trans, trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors

Apostolia M. Tsimberidou, Michelle A. Rudek, David S. Hong, Chaan S. Ng, Jessica Blair, Howard Goldsweig, Razelle Kurzrock

Cancer Chemotherapy and Pharmacology · 2009 · 46 citations · 22 references

DOI

Concepts

References

22

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations

, , +12

ras oncogenes in human cancer: a review.

Joyce Bos · PubMed · 1989 · 5.1K citations

, , +17

Analytical Methods Validation: Bioavailability, Bioequivalence, and Pharmacokinetic Studies

Vinod P. Shah, Kamal K. Midha, Shrikant V. Dighe et al. · Journal of Pharmaceutical Sciences · 1992 · 1.1K citations

, , +14

K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors

David B. Whyte, Paul T. Kirschmeier, Tish Hockenberry et al. · Journal of Biological Chemistry · 1997 · 881 citations · Full text

, , +16

Benzodiazepine Peptidomimetics: Potent Inhibitors of Ras Farnesylation In Animal Cells

Guy L. James, Joseph L. Goldstein, Michael S. Brown et al. · Science · 1993 · 629 citations

, , +15