Concepedia

Mechanism underlying anti-hyperalgesic and anti-allodynic properties of anomalin in both acute and chronic inflammatory pain models in mice through inhibition of NF-κB, MAPKs and CREB signaling cascades

Salman Khan, Omer Shehzad, Jaemoo Chun, Yeong Shik Kim

European Journal of Pharmacology · 2013 · 56 citations · 31 references

References

31

Ethical guidelines for investigations of experimental pain in conscious animals

M. Zimmermann · Pain · 1983 · 7.7K citations

Pain Therapy, Pain Syndrome, Behavioral Sciences +12

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

Zhi‐Ye Zhuang, Peter Gerner, Clifford J. Woolf et al. · Pain · 2005 · 766 citations

Pain Medicine, Erk Kinase, Neuropathic Pain +18

Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine

Zhi-Ye Zhuang, Yasuhiko Kawasaki, Ping-Heng Tan et al. · Brain Behavior and Immunity · 2006 · 357 citations · Full text

Inflammation, Pain Research, Spinal Cord Injury +12

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

Hawon Cho, Young Yang, Jesun Lee et al. · Nature Neuroscience · 2012 · 357 citations

Calcium-activated Chloride Channel, Health Sciences, Neurophysiology +12

Spinal NF‐kB activation induces COX‐2 upregulation and contributes to inflammatory pain hypersensitivity

Kyung‐min Lee, Bong‐Seok Kang, Sun‐Joo Son et al. · European Journal of Neuroscience · 2004 · 248 citations

Pain Disorders, Pain Medicine, Immunology +18