Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine

Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine.

John Bales, D P Higham, Ian Howe et al. · Clinical Chemistry · 1984 · 292 citations

Life Sciences, Biochemistry, Metabolism +13

Proton-nuclear-magnetic-resonance studies of serum, plasma and urine from fasting normal and diabetic subjects

Jeremy K. Nicholson, MargaretE. O'Flynn, Peter J. Sadler et al. · Biochemical Journal · 1984 · 275 citations · Full text

Life Sciences, Biochemistry, Endocrinology +12

High resolution 1H n.m.r. studies of vertebrate blood and plasma

Jeremy K. Nicholson, Michael J. Buckingham, Peter J. Sadler · Biochemical Journal · 1983 · 256 citations · Full text

Natural Sciences, Biochemistry, Chemistry +12

Proton NMR spectra of urine as indicators of renal damage. Mercury-induced nephrotoxicity in rats.

Jeremy K. Nicholson, John A. Timbrell, P J Sadler · Molecular Pharmacology · 1985 · 161 citations

Pharmacy, Biochemistry, Toxicology +17

Urinary excretion of acetaminophen and its metabolites as studied by proton NMR spectroscopy.

John Bales, P J Sadler, Jeremy K. Nicholson et al. · PubMed · 1984 · 134 citations

Pharmacy, Pharmacokinetics, Pharmacology +14