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Xanthorrhizol: A Potential Antibacterial Agent from<i>Curcuma xanthorrhiza</i>against<i>Streptococcus mutans</i>
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2000
Year
Potential Antibacterial AgentJavanese TurmericBioassay-guided IsolationMedicineHerbal MedicinePathologyPhytopharmacologyAntibacterial AgentAntimicrobial TherapyMicrobiologyAntimicrobial AgentsCurcuma Xanthorrhiza Roxb.Antimicrobial CompoundPharmacologyCurcuma XanthorrhizaAntimicrobial ChemotherapyAntimicrobial ResistanceDrug Discovery
Curcuma xanthorrhiza Roxb., commonly known as temu lawak or Javanese turmeric, has been traditionally used in Indonesia for food an medicinal purposes [1]. It has been reported that Curcuma xanthorrhiza confers a variety of biological activities such as antitumor [2], hypotriglyceridaemic [3], anti-inflammatory [4], antibacterial [5], etc. In this research we found that xanthorrhizol (1,3,5,10-bisabolatetraen-3-ol), isolated from Curcuma xanthorrhiza, possessed remarkable anticariogenic activity against Streptococcus mutans.