Catabolic Control of Mammalian Cell Culture

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

Larry Reitzer, Burton M. Wice, David Kennell · Journal of Biological Chemistry · 1979 · 1.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: Effect of nutrient concentration, dilution rate, and pH

William M. Miller, Harvey W. Blanch, C. R. Wilke · Biotechnology and Bioengineering · 1988 · 474 citations

Life Sciences, Biochemistry, Cell Biology +16

The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.

Randall W. Moreadith, A L Lehninger · Journal of Biological Chemistry · 1984 · 412 citations · Full text

Life Sciences, Biochemistry, Cancer Biology +17

Cell and Tissue Culture

Joshua R. C. Brown, John Paul · Transactions of the American Microscopical Society · 1971 · 360 citations

Engineering, Biomedical Engineering, Cell Biology +12

Reduction of waste product excretion via nutrient control: Possible strategies for maximizing product and cell yields on serum in cultures of mammalian cells

Michael W. Glacken, Robert J. Fleischaker, Anthony J. Sinskey · Biotechnology and Bioengineering · 1986 · 346 citations

Life Sciences, Biotechnology, Cell Biology +17