TACE is required for the activation of the EGFR by TGF-α in tumors

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature · 1997 · 3.1K citations

Inflammation, Medicine, Metalloprotein +6

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

Marcia L. Moss, S.-L. Catherine Jin, Marcos E. Milla et al. · Nature · 1997 · 1.6K citations

Protein Expression, Medicine, Disintegrin Metalloproteinase +8

An Essential Role for Ectodomain Shedding in Mammalian Development

Jacques J. Peschon, Jennifer L. Slack, P. Linga Reddy et al. · Science · 1998 · 1.6K citations

MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

Lisa M. Coussens, Christopher L. Tinkle, Douglas Hanahan et al. · Cell · 2000 · 1.3K citations · Full text

Skin Development, Medicine, Photocarcinogenesis +10

A Novel Proteolytic Cleavage Involved in Notch Signaling

Christel Brou, Frédérique Logeat, Neetu Gupta et al. · Molecular Cell · 2000 · 1.1K citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +6