Alkaline Serine Proteinase from <i>Aspergillus fumigatus</i> Has Synergistic Effects on Asp-f-2-Induced Immune Response in Mice

Abstract

In spite of the similar immunological responses in the different groups of mice studied, the results demonstrate enhanced inflammation in the lungs of mice exposed to a combination of both allergens. Allergens with proteinase activity have been found to be involved in airway inflammation and remodeling, which may also apply for Aspergillus-induced allergy.