Non-isotopic in situ detection of mRNA for interleukin-4 in archival human tissue

The use of avidin-biotin interaction in immunoenzymatic techniques.

Jean‐Luc Guesdon, Thérèse Ternynck, Stratis Avraméas · Journal of Histochemistry & Cytochemistry · 1979 · 1.7K citations

Immunocytochemical Technique, Immunology, Pathology +17

Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes.

Pennina R. Langer, Alex A. Waldrop, David C. Ward · Proceedings of the National Academy of Sciences · 1981 · 1.1K citations · Full text

Bioorganic Chemistry, Engineering, Enzymatic Synthesis +17

Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia

Michael Samoszuk, L Nansen · Blood · 1990 · 218 citations · Full text

<i>In vivo</i> cytokine gene expression in T cell subsets of the autoimmune MRL/Mp‐<i>lpr/lpr</i> mouse

Lesley Murray, Rozanne Lee, Christine Martens · European Journal of Immunology · 1990 · 216 citations

Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4⁺ T cells

Andrew J. McKnight, A. Neil Barclay, Don Mason · European Journal of Immunology · 1991 · 210 citations