Nuclear Hypersegmentation in the Myeloma Cells of a Patient with Multiple Myeloma

Abstract

A patient with multiple myeloma in whom the bone marrow plasmablasts showed extensive lobulation is described. In addition to numerous lobes, some of the nuclei had a cerebriform appearance, similar to that observed in Sézary cells. The possible relation of this phenomenon to the expression of the altered function of the malignant cells is discussed.