Zonisamide improves motor function in Parkinson disease

Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial

Olivier Rascol, E. Melamed, Wolfgang H. Oertel et al. · The Lancet · 2005 · 632 citations

Adjunct Therapy, Parkinson Disease, Neuropharmacology +8

Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex

Setsuo Suzuki, Kaori Kawakami, Shigeko Nishimura et al. · Epilepsy Research · 1992 · 269 citations

Cultured Neurons, Health Sciences, Neurophysiology +14

Intermittent vs Continuous Levodopa Administration in Patients With Advanced Parkinson Disease

Fabrizio Stocchi, Laura Vacca, Stefano Ruggieri et al. · Archives of Neurology · 2005 · 224 citations

Effects of zonisamide on dopaminergic system

Motohiro Okada, Shuji Kaneko, Tomoko Hirano et al. · Epilepsy Research · 1995 · 177 citations

Medicine, Neuropharmacology, Neuroscience +3

Mechanisms of T-type calcium channel blockade by zonisamide

Masao Kito, Mitsuo Maehara, Kazuyoshi Watanabe · Seizure · 1996 · 148 citations · Full text

Channelopathies, Medicine, Physiology +4