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Hughlings Jackson predicted that epilepsy would provide an unparallelled opportunity to study the mind and nervous system, an opportunity Penfield and Jasper exploited in their monumental work<i>Epilepsy and the Functional Anatomy of the Human Brain</i>.<sup>1</sup>Subsequent books on the same theme<sup>2,3</sup>were necessarily technical, and focused on complicated research models not designed to display the "window to brain mechanisms" in a manner that could be interesting or easily digested by the student, general medical audience, or even many clinical neurologists or neurological surgeons.<i>Science and Epilepsy</i><sup>4</sup>by O'Leary and Goldring reviewed the influence of epilepsy in neuroscience research, but did not focus on current experimental work. This new effort is written and displayed in a manner that should be understandable by any who have completed medical school physiology, and yet the approach and information are current and detailed enough to be valuable to the physician with clinical or