Digestion · 2009 · 18 citations · 0 references
Life SciencesEndocrinologyPhysiologyGastrointestinal PharmacotherapyNeuroendocrinologyNutritional PhysiologyDigestive PhysiologyGastrointestinal FunctionGastrointestinal MotilityGastrointestinal PathophysiologyGastrointestinal PhysiologyHormone SecretionCholecystokinin PharmacologyGastrointestinal Hormone SecretionGastrointestinal Motility ControlIntestinal Hormone SecretionIntestinal Motility InhibitionIntestinal SecretionRegulation Of Motor ActivitySmall Intestinal Motility
The effects of intravenous administration of secretin and cholecystokinin (CCK) on motility of the human jejunum were investigated with pressure-sensitive radiotelemetering capsules. Secretin inhibited and CCK stimulated the spontaneous motor activity of this part of the small intestine. Raising the dosages of the two hormones caused increasing effects. It seems likely, therefore, that both hormones play a role in the regulation of intestinal motility in man.