Physics in Medicine and Biology · 2011 · 54 citations · 41 references
Natural SciencesBiophysicsNuclear PhysicsRadiation DosimetryRadiation PhysicsLinear Energy TransferMonte Carlo DosimetryMonte Carlo Radiation TransportRadiation Track StructureRadiation Transport In MatterRadiobiological ModelingEnergy DepositionEnergy Deposition TracksEnergy TransferLinear Energy Transfer EffectsMonte Carlo Track SimulationsTrack Structure In WaterTrack Structure ModelingTrack Structure Simulation
This work presents a Monte Carlo study of energy depositions due to protons, alpha particles and carbon ions of the same linear-energy-transfer (LET) in liquid water. The corresponding track structures were generated using the Geant4-DNA toolkit, and the energy deposition spatial distributions were analyzed using an adapted version of the DBSCAN clustering algorithm. Combining the Geant4 simulations and the clustering algorithm it was possible to compare the quality of the different radiation types. The ratios of clustered and single energy depositions are shown versus particle LET and frequency-mean lineal energies. The estimated effect of these types of radiation on biological tissues is then discussed by comparing the results obtained for different particles with the same LET.
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A density-based algorithm for discovering clusters in large spatial Databases with Noise
Martin Ester, Hans‐Peter Kriegel, Jörg Sander et al. · 1996 · 19.1K citations
Geant4 developments and applications
John E. Allison, K. Amako, J. Apostolakis et al. · IEEE Transactions on Nuclear Science · 2006 · 6.9K citations · Full text