A Novel Free Radical Scavenger, Edarabone, Protects Against Cisplatin-Induced Acute Renal Damage in Vitro and in Vivo

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

Ralf Schreck, P. Rieber, Patrick A. Baeuerle · The EMBO Journal · 1991 · 3.8K citations · Full text

Life Sciences, Immunology, Molecular Biology +11

NONDROPLET ULTRASTRUCTURAL DEMONSTRATION OF CYTOCHROME OXIDASE ACTIVITY WITH A POLYMERIZING OSMIOPHILIC REAGENT, DIAMINOBENZIDINE (DAB)

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Life Sciences, Biochemistry, Cell Biology +14

TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

Ganesan Ramesh, William Reeves · Journal of Clinical Investigation · 2002 · 753 citations · Full text

Medicine, Pharmacology, Toxicology +17

Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model.

Shinya Toyokuni, Tomoyuki Tanaka, Yuki Hattori et al. · PubMed · 1997 · 584 citations

Medicine, Cancer Biology, Oncology +8

Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions.

Toshiaki Watanabe, Satoshi Yuki, Mariko Egawa et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 464 citations

Medicine, Neuroscience, Pharmacology +17