Polyaromatic alkaloids from marine invertebrates as cytotoxic compounds and inhibitors of multidrug resistance caused by P-glycoprotein

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 54.9K citations

Cellular Growth, Rapid Colorimetric Assay, Cytotoxicity Assays +11

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi et al. · PubMed · 1981 · 1.5K citations

Chemoprevention Strategy, Vincristine Resistance, Medicine +11

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

Norbert Kartner, Deanna Evernden-Porelle, Grace Bradley et al. · Nature · 1985 · 922 citations

Immunocytochemical Technique, Glycosylation, Medicine +9

Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients.

Robert F. Ozols, Robert E. Cunnion, R W Klecker et al. · Journal of Clinical Oncology · 1987 · 426 citations

Heart Failure, Gynecology, Pharmacotherapy +17

Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.

John M. Zamora, Homer L. Pearce, William T. Beck · Molecular Pharmacology · 1988 · 414 citations