Receptor Activator of Nuclear Factor κB Ligand (RANKL)/Osteoprotegerin (OPG) Ratio Is Increased in Severe Osteolysis

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

David L. Lacey, Emma Timms, Hong‐Lin Tan et al. · Cell · 1998 · 5.5K citations · Full text

Medicine, Cell Biology, Bone Metabolism +13

Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

W. Scott Simonet, Dave Lacey, Colin R. Dunstan et al. · Cell · 1997 · 5.1K citations · Full text

Medicine, Biochemistry, Molecular Biology +13

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Hisataka Yasuda, Nobuyuki Shima, N. Nakagawa et al. · Proceedings of the National Academy of Sciences · 1998 · 4.3K citations

Medicine, Cell Biology, Molecular Biology +15

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Young‐Yun Kong, Ulrich Feige, Iidiko Sarosi et al. · Nature · 1999 · 1.9K citations

Medicine, Immunology, Pathobiology +17

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

Hailing Hsu, David L. Lacey, Colin R. Dunstan et al. · Proceedings of the National Academy of Sciences · 1999 · 1.6K citations

Life Sciences, Cell Biology, Molecular Biology +17