Variants in the Netrin-1 Receptor UNC5C Prevent Apoptosis and Increase Risk of Familial Colorectal Cancer

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.

C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton et al. · PubMed · 1998 · 4.1K citations

Life Sciences, Genetics, Oncology +17

Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)

Heather Hampel, Wendy L. Frankel, Edward W. Martin et al. · New England Journal of Medicine · 2005 · 1.4K citations · Full text

Medicine, Genetics, Molecular Genetics +14

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

Tito Serafini, Sophia A. Colamarino, E. David Leonardo et al. · Cell · 1996 · 1.3K citations · Full text

Life Sciences, Developmental Biology, Neuroscience +14

Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

Lauri A. Aaltonen, Reijo Salovaara, Paula Kristo et al. · New England Journal of Medicine · 1998 · 1.2K citations · Full text

Medicine, Genetics, Oncology +17

Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor

Kazuko Keino‐Masu, Masayuki Masu, Lindsay Hinck et al. · Cell · 1996 · 1K citations · Full text

Life Sciences, Molecular Biology, Oncology +10