British Journal of Ophthalmology · 1991 · 69 citations · 6 references
MedicineOncologyOphthalmologyMetastasisOcular DiseaseOcular OncologyChoroidal TumorsIntraocular TumorsMelanocytic TumorsOcular TumorsUveal MelanomaLaser PhotocoagulationLate ComplicationsMalignant Choroidal TumorsMalignant Ocular TumorsOcular MetastasisRetinal PhotocoagulationUveal Melanoma Metastasis
Thirty nine patients suffering from juxtapapillary choroidal melanoma were treated with Ru-106/Rh-106 beta-ray plaques. The tumoricidal dose was 100 Gy at the apex of the tumour within 7-14 days. Additional photocoagulation was performed in 12 eyes. The irradiated eyes of three patients had to be enucleated, seven patients died, five of them (12.8%) from metastases. Thirty two (82%) patients are alive and 29 (74%) have a seeing eye. From the whole series 20 (51%) developed flat scars and 11 (29%) patients retained a visual acuity of 0.5-1.0. Radiogenic late complications with damage to the optic nerve and macula were the main causes of visual deterioration.
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Evangelos S. Gragoudas, Michael Goitein, Lynn Verhey et al. · Ophthalmology · 1980 · 220 citations
Uveal Melanomas Near the Optic Disc or Fovea
Johanna M. Seddon, Evangelos S. Gragoudas, Kathleen M. Egan et al. · Ophthalmology · 1987 · 112 citations
Medicine, Oncology, Ophthalmology +14
Irradiation of Choroidal Melanoma With Iodine 125 Ophthalmic Plaque
Samuel Packer, Marvin Rotman, Ralph G. Fairchild et al. · Archives of Ophthalmology · 1980 · 76 citations
Medicine, Oncology, Ophthalmology +17
Local radiotherapy in the treatment of malignant melanoma of the choroid.
MacFaul Pa · PubMed · 1977 · 59 citations