Synthesis of novel 5-substituted pyrazole derivatives as cannabinoid antagonists

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

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Pharmacotherapy, Experimental Pharmacology, Cannabinoid Pharmacology +18

Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.

Vincent M. Showalter, David M. Compton, BR Martin et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 570 citations

Palladium-catalyzed inter- and intramolecular cross-coupling reactions of B-alkyl-9-borabicyclo[3.3.1]nonane derivatives with 1-halo-1-alkenes or haloarenes. Syntheses of functionalized alkenes, arenes, and cycloalkenes via a hydroboration-coupling sequence

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Cross-coupling Reaction, Engineering, Natural Sciences +12

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.

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Structure−Activity Relationships of Pyrazole Derivatives as Cannabinoid Receptor Antagonists

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