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Utilization of p40 (ΔNp63) with p63 and Cytokeratin 5/6 Immunohistochemistry in Non-Small Cell Lung Carcinoma Fine-Needle Aspiration Biopsy

Brian T. Collins, Jeff F. Wang, Cory T. Bernadt

Acta Cytologica · 2013 · 13 citations · 14 references

DOIFull text

Open access

Abstract

For NSCCA, p40 had 89% sensitivity and 100% specificity compared to p63 with 86% sensitivity and 96% specificity and CK5/6 with 100% sensitivity and 96% specificity. In the evaluation of FNA biopsy for pulmonary NSCCA, p40 is a useful IHC marker for neoplastic subclassification, with better specificity in comparison to p63.

References

14

p40 (ΔNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma

Justin A. Bishop, Julie Teruya‐Feldstein, William H. Westra et al. · Modern Pathology · 2011 · 380 citations

, , +8

Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens

Natasha Rekhtman, Daphne Ang, Camelia S. Sima et al. · Modern Pathology · 2011 · 330 citations · Full text

, , +15

Subclassification of Non-small Cell Lung Carcinomas Lacking Morphologic Differentiation on Biopsy Specimens

Sanjay Mukhopadhyay, Anna-Luise A. Katzenstein · The American Journal of Surgical Pathology · 2010 · 307 citations

, , +21

Accurate Classification of Non–Small Cell Lung Carcinoma Using a Novel MicroRNA-Based Approach

Justin A. Bishop, Hila Benjamin, Hila Cholakh et al. · Clinical Cancer Research · 2010 · 224 citations · Full text

Optimal Immunohistochemical Markers For Distinguishing Lung Adenocarcinomas From Squamous Cell Carcinomas in Small Tumor Samples

Jefferson Terry, Samuel Leung, Janessa Laskin et al. · The American Journal of Surgical Pathology · 2010 · 195 citations

, , +17