Ocular Immunology and Inflammation · 2006 · 16 citations · 4 references
MedicineInfectious DiseasesMicrobiologyMedical MicrobiologyMycologyPediatric DermatologyCorneal InfectionCorneal PathologyCorneal TraumaFungal DiagnosticsFungal InfectionsMicrobial KeratitisCandida Keratitis TreatmentCorneal MycosesFluconazole TherapyInfection Risk FactorsMycotic KeratitisOcular MycosisOcular Surface Fungal InfectionTopical Corticosteroid-associated Fungal Infection
PURPOSE: To describe a previously unreported case of polymicrobial mycotic keratitis caused by an association between Candida lusitaniae, C. parapsilosis, and Geotrichum candidum. METHODS: A three-year-old child with an antecedent trauma with vegetable matter and a prolonged use of corticosteroid eyedrops developed fungal keratitis. RESULTS: The isolates of the corneal scraping using Sabaraud dextrose agar grew C. lusitaniae, C. parapsilosis, and G. candidum. After topical 0.2% and systemic fluconazole treatment, the corneal lesion resolved with no recurrence. CONCLUSIONS: Corneal trauma with vegetables and the indiscriminate use of corticosteroids are important risk factors for mycotic keratitis. A combination of topical 0.2% and systemic fluconazole therapy was effective in the treatment of this mycotic association. This is the first report of fungal keratitis caused by C. lusitaniae and G. candidum.
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Anita Panda, Namrata Sharma, Gopal K. Das et al. · Cornea · 1997 · 116 citations
Microbial Keratitis in Children
Thomas Clinch, Floretino E. Palmon, Matthew J. Robinson et al. · American Journal of Ophthalmology · 1994 · 66 citations
Oral Ketoconazole Therapy for Keratomycosis
Yasuhisa Ishibashi · American Journal of Ophthalmology · 1983 · 50 citations
Medicine, Dermatology, Pharmacology +12