Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: Regulation of expression and activation by interleukin-1 and tumor necrosis factor ? - Concepedia

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Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: Regulation of expression and activation by interleukin-1 and tumor necrosis factor ?

68

Citations

35

References

2001

Year

Kurt Redlich, Hans P. Kiener, Georg Schett, M Tohidast-Akrad, Edgar Selzer, I Radda, Georg Stummvoll, Carl W. Steiner, Marion Gr�ger, Peter Bitzan,

Arthritis & Rheumatism

Abstract

The overexpression of Ets-1 observed in RA synovial tissue appears to be caused by TNFalpha and IL-1, suggesting that Ets-1 may be an important factor in the cytokine-mediated inflammatory and destructive cascade characteristic of RA.

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