Concepedia

Alternative splicing and proteolytic rupture contribute to the generation of soluble IL-6 receptors (sIL-6R) in rheumatoid arthritis

José Ramón Lamas, Luis Rodríguez‐Rodríguez, Pilar Tornero-Esteban, E. Villafuertes, J. Hoyas, Lydia Abásolo, Jezabel Varadé, Roberto Álvarez‐Lafuente, Elena Urcelay, Benjamín Fernández‐Gutiérrez

Cytokine · 2013 · 22 citations · 11 references

DOI

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References

11

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

Athena Chalaris, Björn Rabe, Krzysztof Paliga et al. · Blood · 2007 · 323 citations · Full text

, , +14

The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site.

Jürgen Müllberg, Walter OBERTHÜR, F. Lottspeich et al. · The Journal of Immunology · 1994 · 268 citations

, , +15

Cutting Edge: Soluble IL-6R Is Produced by IL-6R Ectodomain Shedding in Activated CD4 T Cells

Eva M. Briso, Oliver Dienz, Mercedes Rincón · The Journal of Immunology · 2008 · 165 citations · Full text

, , +15

Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced

Johnah C. Galicia, H. Tai, Y. Komatsu et al. · Genes and Immunity · 2004 · 145 citations

, , +11

Concentrations and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid.

Alain Desgeorges, Cem Gabay, Paolo Silacci et al. · PubMed · 1997 · 135 citations

, , +12