Behavioral Effects of Acute and Chronic Fluoxetine in Wistar–Kyoto Rats

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

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Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

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The use of a plus-maze to measure anxiety in the mouse

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Development of a Strain of Spontaneously Hypertensive Rats

Kôzô Okamoto, Kyuzo Aoki · Japanese Circulation Journal · 1963 · 2.5K citations

Life Sciences, Animal Sciences, Physiology +12

A multiple-test study of anxiety-related behaviours in six inbred rat strains

André Ramos, Olivier Berton, Pierre Mormède et al. · Behavioural Brain Research · 1997 · 501 citations

Social Sciences, Behavioral Sciences, Psychology +7