Complications Associated With Prolonged Hypertonic Saline Therapy in Children With Elevated Intracranial Pressure

Abstract

Children treated by continuous hypertonic saline infusion for intracranial hypertension whose serum sodium levels exceeded certain thresholds experienced significantly more events of acute renal failure, thrombocytopenia, neutropenia, anemia, and acute respiratory distress syndrome than those whose sodium level was maintained below these thresholds.