The intracellular domain of the amyloid precursor protein (AICD) enhances the p53-mediated apoptosis

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature · 1987 · 4.6K citations

Alzheimer's Disease, Protein Folding, Cell-surface Receptor +7

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

Daniel Burdick, AJ Walencewicz, CG Glabe et al. · Journal of Neuroscience · 1993 · 1.4K citations · Full text

Beta-amyloid Peptides, Molecular Biology, Time Peptides +19

Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis

Tsuyoshi Ikura, Vasily Ogryzko, Mikhaïl Grigoriev et al. · Cell · 2000 · 1K citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +7

Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein

Sung Hee Baek, Kenneth A. Ohgi, David W. Rose et al. · Cell · 2002 · 553 citations · Full text

Transcriptional Regulation, Protein Function, Signal Transduction +11

The Phosphotyrosine Interaction Domains of X11 and FE65 Bind to Distinct Sites on the YENPTY Motif of Amyloid Precursor Protein

Jean‐Paul Borg, James Ooi, Efrat Levy et al. · Molecular and Cellular Biology · 1996 · 475 citations · Full text

Protein Assembly, Molecular Biology, Cytoskeleton +20