5-Oxo-octanoic acid and 5-oxo-octanal, precursors of coniine

Abstract

The administration of [6-14C]-5-oxo-octanoic acid or [6-14C]-5-oxo-octanal to hemlock plants (Conium maculatum) resulted in the formation of [1′-14C]coniine, with high incorporations of activity as compared with [1-14C]acetate and [1-14C]octanoic acid, suggesting that they are the immediate precursors of coniine.