Concepedia

Comparative Genomics of the Mucoid and Nonmucoid Strains of Streptococcus pyogenes, Isolated from the Same Patient with Streptococcal Meningitis

Haruno Yoshida, Yasuhito Ishigaki, Asako Takizawa, Kunihiko Moro, Yuki Kishi, Takashi Takahashi, Hidenori Matsui

Genome Announcements · 2015 · 16 citations · 7 references

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Abstract

Mucoid (MTB313) and nonmucoid (MTB314) strains of group A streptococcus emm type 1 were simultaneously isolated from a single patient suffering from streptococcal meningitis. Whole-genome sequencing revealed that MTB313 carried a nucleotide substitution within rocA, which generated an amber termination codon.

References

7

Complete genome sequence of an M1 strain of <i>Streptococcus pyogenes</i>

Joseph J. Ferretti, W. Michael McShan, Dragana Ajdić et al. · Proceedings of the National Academy of Sciences · 2001 · 942 citations · Full text

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Virulence control in group A <i>Streptococcus</i> by a two-component gene regulatory system: Global expression profiling and <i>in vivo</i> infection modeling

Morag Graham, Laura M. Smoot, Cristi A. Lux Migliaccio et al. · Proceedings of the National Academy of Sciences · 2002 · 392 citations · Full text

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Evolutionary Origin and Emergence of a Highly Successful Clone of Serotype M1 Group A<i>Streptococcus</i>Involved Multiple Horizontal Gene Transfer Events

Paul Sumby, Steve F. Porcella, Andres G. Madrigal et al. · The Journal of Infectious Diseases · 2005 · 372 citations · Full text

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Identification of<i>rocA</i>, a Positive Regulator of<i>covR</i>Expression in the Group A Streptococcus

Indranil Biswas, June R. Scott · Journal of Bacteriology · 2003 · 86 citations

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RocA Truncation Underpins Hyper-Encapsulation, Carriage Longevity and Transmissibility of Serotype M18 Group A Streptococci

Nicola N. Lynskey, David Goulding, Magdalena Gierula et al. · PLoS Pathogens · 2013 · 68 citations · Full text

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