Journal of Clinical Investigation · 1956 · 230 citations · 20 references
Abnormal thyroid function profoundly alters calcium metabolism. These changes could not be ascribed to elevation of metabolism per se (1) acidosis (2) or vitarmin D deficiency (3); they were observed even in the absence of the para- thyroid glands (4, 5). In addition, roentgeno- graphic evidence of skeletal demineralization has been described in patients with thyrotoxicosis (6).
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