The enamel knot as a signaling center in the developing mouse tooth

Sonic hedgehog mediates the polarizing activity of the ZPA

Robert D. Riddle, Randy L. Johnson, Ed Laufer et al. · Cell · 1993 · 2.3K citations

Biology, Developmental Biology, Neuroanatomy +5

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

Yann Echelard, Douglas J. Epstein, Benoit St‐Jacques et al. · Cell · 1993 · 2.2K citations

Molecular Neuroscience, Developmental Biology, Signal Transduction +14

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

Ichiro Satokata, Richard L. Maas · Nature Genetics · 1994 · 1.3K citations

Knockout Mouse, Developmental Biology, Tissue Development +10

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

C van Genderen, Ryoichi Okamura, Isabel Fariñas et al. · Genes & Development · 1994 · 963 citations · Full text

Lymphocyte Development, Inductive Epithelial-mesenchymal Interactions, Immunology +20

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

Seppo Vainio, Irina Karavanova, Adrian K. Jowett et al. · Cell · 1993 · 905 citations

Regenerative Medicine, Odontology, Developmental Biology +12