AIDS Research and Human Retroviruses · 2003 · 34 citations · 16 references
Life SciencesMicrobiologyMolecular GeneticsMolecular EvolutionRecombinationVirologyViral EvolutionViral GeneticsViral GenomicsViral InfectionsViral RecombinationVirus EvolutionPhylogenetic Recombination AnalysisPhylogenetic Tree InferencePhylogenetic Virus ClassificationPhylogenomics Of VirusesRecombination In Emerging VirusesSubtypingVirus Evolution AnalysisVirus Evolutionary Relationships
On the basis of partial env and gag subtyping, we documented that the majority of HIV-1 strains circulating in Niger were CRF02-AG (54.3%) or CRF06-cpx (18.1%) and that 9% of the samples were possible recombinants between CRF02 and CRF06. To determine in more detail the precise structure of these viruses we sequenced the full-length genomes for three such strains (97NE-003, 00NE-036, and 00NE-095). From the bootscan and phylogenetic tree analysis it is evident that the new viruses are the result of recombination events between CRF02-AG and CRF06-cpx strains. Importantly, each virus had a different complex recombinant structure with multiple breakpoints, leading to viruses with complex mosaic patterns.
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Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text
A Patient with HIV-1 Superinfection
Stéphanie Jost, Marie‐Charlotte Bernard, Laurent Kaiser et al. · New England Journal of Medicine · 2002 · 245 citations · Full text
Genetic diversity of HIV-1: the moving target.
Marc Peeters, Paul M. Sharp · PubMed · 2000 · 199 citations