Highly selective σ receptor ligands elevate inositol 1,4,5-trisphosphate production in rat cardiac myocytes

Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

J Watras, Barbara E. Ehrlich · Nature · 1991 · 1.7K citations

Life Sciences, Neurobiology, Neuroscience +16

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

Markus Hanner, Fabian F. Moebius, Astrid Flandorfer et al. · Proceedings of the National Academy of Sciences · 1996 · 908 citations

Medicine, Biochemistry, Pharmacology +13

Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.

Bertold J. Vilner, Christy S. John, W D Bowen · PubMed · 1995 · 488 citations

Medicine, Oncology, Pharmacology +10

Cloning and Functional Expression of the Human Type 1 Sigma Receptor (hSigmaR1)

Ramesh Kekuda, Puttur D. Prasad, You-Jun Fei et al. · Biochemical and Biophysical Research Communications · 1996 · 415 citations

Life Sciences, Genetics, Molecular Biology +5

Actions of sympathomimetic amines on the Ca2+ transients and contractions of rabbit myocardium: reciprocal changes in myofibrillar responsiveness to Ca2+ mediated through alpha- and beta-adrenoceptors.

Makoto Endoh, John R. Blinks · Circulation Research · 1988 · 338 citations

Life Sciences, Pharmacology, Physiology +13