Iron-catalyzed Benzannulation Reactions of 2-Alkylbenzaldehydes and Alkynes Leading to Naphthalene Derivatives

Abstract

An efficient and practical method for the synthesis of naphthalene derivatives via Fe(III)-catalyzed benzannulation of 2-(2-oxoethyl)-benzaldehydes and alkynes has been developed. The system holds the advantages of cheap catalysts, wide substrate scope, and mild reaction conditions.